William M Perlstein

William M Perlstein, Ph.D.

Associate Professor

Department: Department of Clinical and Health Psychology
Business Phone: (352) 273-6139
Business Email: wmp@phhp.ufl.edu

Accomplishments

Dean’s Citation Paper Award, to acknowledge innovation and excellence in research (http://chp.phhp.ufl.edu/2012/09/26/william-perlstein-ph-d-deans-citation-paper-award/)
2012 · College of Public Health and Health Professions, University of Florida
NARSAD Young Investigator Award
2001 · National Alliance for Research in Schizophrenia and Depression (NARSAD), now Brain and Behavior Research Foundation
Research Mentor Award, Department of Clinical & Health Psychology
2001 · Department of Clinical and Health Psychology, University of Florida
NIMH Mentored Research Scientist Development Award (K01)
2000-2004 · National Institute of Mental Health (NIMH)
NIMH Post-Doctoral Fellowship (T32), Clinical Research Training in Psychiatry
1997 · University of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Institute & Clinic (WPICP
NARSAD Young Investigator Award
1996 · National Alliance for Research in Schizophrenia and Depression (NARSAD)–now Brain and Behavior Research Foundation
NIMH Post-Doctoral Fellowship (T32), Clinical Research Training in Psychiatry
1996 · University of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Institute & Clinic (WPICP
NIMH Post-Doctoral Fellowship (T32), Clinical Research Training in Psychiatry
1995 · University of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Institute & Clinic (WPICP
NIMH Post-Doctoral Fellowship (T32), Clinical Research Training in Psychiatry
1994 · University of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Institute & Clinic (WPICP
Nominated by University of Delaware Psychology Department faculty for University-wide Ph.D. dissertation award
1994 · Department of Psychology, University of Delaware

Teaching Profile

Courses Taught
2019-2023
CLP4302 Introduction to Clinical Psychology
2013-2023
CLP6971 Research for Master’s Thesis
2019-2023
CLP3911 Introduction to Clinical Research
2009-2011,2013-2021,2019-2025
CLP7980 Research for Doctoral Dissertation
2007,2009-2023
CLP7934 Special Topics In Clinical Psychology
2009-2010,2013-2025
CLP7979 Advanced Research
2020
CLP6430 Clinical Psychological Assessment
2020
CLP6940 Supervised Teaching
2015-2019
HSC4608L Critical Thinking in Health Care
2018
GMS7979 Advanced Research
2013-2016,2018-2022,2022
CLP6947 Practicum in Intervention
2015,2022-2024
CLP6943 Core Practicum in Clinical Psychology
2015
CLP6905 Individual Work
2014
HSC4905 Individual Study
2012
GMS7795 Special Topics in Neuroscience
2008
HSC4970 Senior Honors Thesis
2021-2024
CLP6945 Advanced Practicum in Neuropsychology
Teaching Philosophy
Dr. Perlstein is highly invested in both classroom teaching (undergraduate and graduate) and clinical teaching/supervision.

Clinical Profile

Specialties
  • Psychology
Subspecialties
  • Clinical Health Psychology
Areas of Interest
  • Generalized anxiety disorder
  • Neurosciences
  • Traumatic Brain Injury

Research Profile

Dr. Perlstein’s research interests include Cognitive Neuroscience, Experimental Psychopathology, Emotion Neuroscience, Anxiety Disorders, Traumatic Brain Injury (including cognitive neuroscience and cognitive rehabilitation), psychophysiology (scalp-recorded brain event-related potentials; ERPs), functional neuroimaging (including functional magnetic resonance imaging (fMRI).

Dr. Perlstein has published per-reviewed papers in highly-respected scientific journals, including Nature and the Proceedings of the National Academy of Sciences (PNAS).

Areas of Interest
  • Cognitive neuroscience, cognitive neuroscience of Traumatic brain injury (TBI), TBI cognitive rehabilitation, affective neuroscience
Open Researcher and Contributor ID (ORCID)

0000-0003-2549-0846

Publications

2023
Executive function improvement in response to meta-cognitive training in chronic mTBI / PTSD
Frontiers in Rehabilitation Sciences. 4 [DOI] 10.3389/fresc.2023.1189292. [PMID] 37484602.
2020
Negative health consequences of pain catastrophizing among retired National Football League athletes.
Health psychology : official journal of the Division of Health Psychology, American Psychological Association. 39(5):452-462 [DOI] 10.1037/hea0000847. [PMID] 31999177.
2020
The influence of traumatic brain injury on the allocation of vertical spatial attention.
Journal of clinical and experimental neuropsychology. 42(1):101-110 [DOI] 10.1080/13803395.2019.1685650. [PMID] 31665971.
2019
Prevalence and Correlates of Psychological Distress among Retired Elite Athletes: A Systematic Review.
International review of sport and exercise psychology. 12(1):265-294 [DOI] 10.1080/1750984X.2018.1469162. [PMID] 31217807.
2018
Gray Matter Changes Following Cognitive Behavioral Therapy for Patients With Comorbid Fibromyalgia and Insomnia: A Pilot Study.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 14(9):1595-1603 [DOI] 10.5664/jcsm.7344. [PMID] 30176973.
2018
Socioeconomic Status and Race Outperform Concussion History and Sport Participation in Predicting Collegiate Athlete Baseline Neurocognitive Scores.
Journal of the International Neuropsychological Society : JINS. 24(1):1-10 [DOI] 10.1017/S1355617717000716. [PMID] 28791942.
2017
Low-to-Moderate Alcohol Consumption is Associated With Hippocampal Volume in Fibromyalgia and Insomnia.
Behavioral sleep medicine. 15(6):438-450 [DOI] 10.1080/15402002.2016.1150279. [PMID] 27144807.
2016
An Event-Related Potential Investigation of the Effects of Age on Alerting, Orienting, and Executive Function.
Frontiers in aging neuroscience. 8 [DOI] 10.3389/fnagi.2016.00099. [PMID] 27242511.
2016
Apathy, Novelty Processing, and the P3 Potential in Parkinson’s Disease.
Frontiers in neurology. 7 [DOI] 10.3389/fneur.2016.00095. [PMID] 27445962.
2016
Orbitofrontal Cortex and the Early Processing of Visual Novelty in Healthy Aging.
Frontiers in aging neuroscience. 8 [DOI] 10.3389/fnagi.2016.00101. [PMID] 27199744.
2015
Fibromyalgia patients have reduced hippocampal volume compared with healthy controls.
Journal of pain research. 8:47-52 [DOI] 10.2147/JPR.S71959. [PMID] 25674013.
2015
Sleep is associated with task-negative brain activity in fibromyalgia participants with comorbid chronic insomnia.
Journal of pain research. 8:819-27 [DOI] 10.2147/JPR.S87501. [PMID] 26648751.
2015
Visuospatial attention after traumatic brain injury: The role of hemispheric specialization.
Brain injury. 29(13-14):1617-29 [DOI] 10.3109/02699052.2015.1075155. [PMID] 26451899.
2014
Bilateral Hippocampal Volume Reductions in Fibromyalgia
Journal of Pain. 15(4, 1)
2014
Immediate changes after manual therapy in resting-state functional connectivity as measured by functional magnetic resonance imaging in participants with induced low back pain.
Journal of manipulative and physiological therapeutics. 37(9):614-27 [DOI] 10.1016/j.jmpt.2014.09.001. [PMID] 25284739.
2014
Response to goal management training in veterans with blast-related mild traumatic brain injury.
Journal of rehabilitation research and development. 51(10):1555-66 [DOI] 10.1682/JRRD.2013.12.0266. [PMID] 25860148.
2013
Chronic Resveratrol Supplementation and Brain Oxygenation: a Pilot Study
Gerontologist. 53(1)
2013
Functional connectivity of the default mode network and its association with pain networks in irritable bowel patients assessed via lidocaine treatment.
The journal of pain. 14(10):1077-87 [DOI] 10.1016/j.jpain.2013.04.003. [PMID] 23743257.
2013
Regional Gray Matter Predicts Placebo Response: a Study of Endogenous Pain Modulation in Healthy Individuals
Journal of Pain. 14
2013
Structural and functional changes of the cingulate gyrus following traumatic brain injury: relation to attention and executive skills.
Journal of the International Neuropsychological Society : JINS. 19(8):899-910 [DOI] 10.1017/S135561771300074X. [PMID] 23845701.
2013
The late positive potential, emotion and apathy in Parkinson’s disease.
Neuropsychologia. 51(5):960-6 [DOI] 10.1016/j.neuropsychologia.2013.01.001. [PMID] 23320979.
2013
Within-session practice eliminates age differences in cognitive control.
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition. 20(5):522-31 [DOI] 10.1080/13825585.2012.736469. [PMID] 23116428.
2012
Cognition Results From the Resveratrol for Improved Performance in Elders (Ripe) Trial
Gerontologist. 52
2012
Effective connectivity among brain regions associated with slow temporal summation of C-fiber-evoked pain in fibromyalgia patients and healthy controls.
The journal of pain. 13(4):390-400 [DOI] 10.1016/j.jpain.2012.01.002. [PMID] 22480771.
2012
Sleep Predicts Resting Brain Activity in Fibromyalgia Participants With Insomnia
Sleep. 35
2011
Detecting Emotional Significance: the Late Positive Potential in Parkinson’S Disease
Psychophysiology. 48
2011
Error-related processing following severe traumatic brain injury: an event-related functional magnetic resonance imaging (fMRI) study.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 82(1):97-106 [DOI] 10.1016/j.ijpsycho.2011.06.019. [PMID] 21756946.
2011
Feeling Antsy About the “Golden Years?” An Event-Related Potential Investigation of the Effects of Age On Three Interactive Attentional Networks
Psychophysiology. 48
2011
Gray matter volumes of pain-related brain areas are decreased in fibromyalgia syndrome.
The journal of pain. 12(4):436-43 [DOI] 10.1016/j.jpain.2010.10.003. [PMID] 21146463.
2011
Predictors of performance monitoring abilities following traumatic brain injury: the influence of negative affect and cognitive sequelae.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 82(1):61-8 [DOI] 10.1016/j.ijpsycho.2011.02.001. [PMID] 21315777.
2011
Psychophysiology and brain imaging of cognition and affect following traumatic brain injury: an overview of the special issue.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 82(1):1-3 [DOI] 10.1016/j.ijpsycho.2011.07.013. [PMID] 21820016.
2010
Operating characteristics of executive functioning tests following traumatic brain injury.
The Clinical neuropsychologist. 24(8):1292-308 [DOI] 10.1080/13854046.2010.528452. [PMID] 21069617.
2009
Awareness of deficits and error processing after traumatic brain injury.
Neuroreport. 20(16):1486-90 [DOI] 10.1097/WNR.0b013e32833283fe. [PMID] 19809369.
2009
Conflict adaptation and cognitive control adjustments following traumatic brain injury.
Journal of the International Neuropsychological Society : JINS. 15(6):927-37 [DOI] 10.1017/S1355617709990701. [PMID] 19765356.
2009
Double jeopardy! The additive consequences of negative affect on performance-monitoring decrements following traumatic brain injury.
Neuropsychology. 23(4):433-44 [DOI] 10.1037/a0015723. [PMID] 19586208.
2009
Neural substrates of object identification: Functional magnetic resonance imaging evidence that category and visual attribute contribute to semantic knowledge.
Journal of the International Neuropsychological Society : JINS. 15(2):169-81 [DOI] 10.1017/S1355617709090468. [PMID] 19232155.
2009
Neural time course of conflict adaptation effects on the Stroop task.
Neuropsychologia. 47(3):663-70 [DOI] 10.1016/j.neuropsychologia.2008.11.013. [PMID] 19071142.
2009
Widespread hyperalgesia in irritable bowel syndrome is dynamically maintained by tonic visceral impulse input and placebo/nocebo factors: evidence from human psychophysics, animal models, and neuroimaging.
NeuroImage. 47(3):995-1001 [DOI] 10.1016/j.neuroimage.2009.04.028. [PMID] 19375508.
2008
Age-related changes in word retrieval: role of bilateral frontal and subcortical networks.
Neurobiology of aging. 29(3):436-51 [PMID] 17147975.
2008
Brain activity associated with slow temporal summation of C-fiber evoked pain in fibromyalgia patients and healthy controls.
European journal of pain (London, England). 12(8):1078-89 [DOI] 10.1016/j.ejpain.2008.02.002. [PMID] 18367419.
2008
The dynamic mechanisms of placebo induced analgesia: Evidence of sustained and transient regional involvement.
Pain. 139(3):660-669 [DOI] 10.1016/j.pain.2008.07.025. [PMID] 18804916.
2007
Brain activity related to temporal summation of C-fiber evoked pain.
Pain. 129(1-2):130-42 [PMID] 17156923.
2007
Functional brain interactions that serve cognitive-affective processing during pain and placebo analgesia.
NeuroImage. 38(4):720-9 [PMID] 17904390.
2007
Individualized piano instruction enhances executive functioning and working memory in older adults.
Aging & mental health. 11(4):464-71 [PMID] 17612811.
2007
Performance monitoring, error processing, and evaluative control following severe TBI.
Journal of the International Neuropsychological Society : JINS. 13(6):961-71 [PMID] 17942014.
2007
Placebo analgesia is accompanied by large reductions in pain-related brain activity in irritable bowel syndrome patients.
Pain. 127(1-2):63-72 [PMID] 16963184.
2007
Reward context sensitivity impairment following severe TBI: an event-related potential investigation.
Journal of the International Neuropsychological Society : JINS. 13(4):615-25 [PMID] 17521495.
2006
Affective context-induced modulation of the error-related negativity.
Neuroreport. 17(3):329-33 [PMID] 16462607.
2006
Cognitive control impairments in traumatic brain injury.
Journal of clinical and experimental neuropsychology. 28(6):968-86 [PMID] 16822736.
2006
Temporal dissociation of components of cognitive control dysfunction in severe TBI: ERPs and the cued-Stroop task.
Neuropsychologia. 44(2):260-74 [PMID] 15979655.
2005
Cognitive control in closed head injury: context maintenance dysfunction or prepotent response inhibition deficit?
Neuropsychology. 19(5):578-90 [PMID] 16187876.
2004
Parametric manipulation of working memory load in traumatic brain injury: behavioral and neural correlates.
Journal of the International Neuropsychological Society : JINS. 10(5):724-41 [PMID] 15327720.
2003
Prefrontal cortex dysfunction mediates deficits in working memory and prepotent responding in schizophrenia.
Biological psychiatry. 53(1):25-38 [PMID] 12513942.
2003
Steady-state visual evoked potentials reveal frontally-mediated working memory activity in humans.
Neuroscience letters. 342(3):191-5 [PMID] 12757897.
2002
Dissociation in human prefrontal cortex of affective influences on working memory-related activity.
Proceedings of the National Academy of Sciences of the United States of America. 99(3):1736-41 [PMID] 11818573.
2001
Prepulse effects as a function of cortical projection system.
Biological psychology. 56(2):83-111 [PMID] 11334698.
2001
Relation of prefrontal cortex dysfunction to working memory and symptoms in schizophrenia.
The American journal of psychiatry. 158(7):1105-13 [PMID] 11431233.
1999
Increased stroop facilitation effects in schizophrenia are not due to increased automatic spreading activation.
Schizophrenia research. 39(1):51-64 [PMID] 10480667.
1998
Functional hypofrontality and working memory dysfunction in schizophrenia.
The American journal of psychiatry. 155(9):1285-7 [PMID] 9734557.
1998
Selective pharmacological activation of limbic structures in human volunteers: a positron emission tomography study.
The Journal of neuropsychiatry and clinical neurosciences. 10(2):148-59 [PMID] 9608403.
1998
The Stroop task and attention deficits in schizophrenia: a critical evaluation of card and single-trial Stroop methodologies.
Neuropsychology. 12(3):414-25 [PMID] 9673997.
1997
Anxiety disorders and the syndrome of chest pain with normal coronary arteries: prevalence and pathophysiology.
The Journal of clinical psychiatry. 58 Suppl 3:70-3; discussion 74 [PMID] 9133495.
1997
Pharmacologic activation of limbic structures and neuroimaging studies of emotions.
The Journal of clinical psychiatry. 58 Suppl 16:13-5 [PMID] 9430504.
1997
Temporal dynamics of brain activation during a working memory task.
Nature. 386(6625):604-8 [PMID] 9121583.
1993
Lead stimulation effects on reflex blink, exogenous brain potentials, and loudness judgments.
Psychophysiology. 30(4):347-58 [PMID] 8327620.
1990
Sensation-seeking: electrodermal and behavioral effects of stimulus content and intensity.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 9(2):179-88 [PMID] 2228752.
1987
The P300 metric in schizophrenia: effects of probability and modality.
Electroencephalography and clinical neurophysiology. Supplement. 40:670-4 [PMID] 2891497.

Grants

Nov 2022 – Dec 2023
IPA for William Perlstein
Role: Principal Investigator
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Sep 2011 – Mar 2016
Florida Trauma Rehabilitation Center for Returning Military Personnel
Role: Project Manager
Funding: US DEPT OF DEFENSE
Jul 2008 – Dec 2020
TO SUPPORT RESEARCH IN THE CLINICAL-COGNITIVE NEUROSCIENCE LABORATORY
Role: Principal Investigator
Funding: **UF FOU UNRESTRICTED DONATION
Jul 2007 – Aug 2016
Clinical and Translational Science Institute
Role: Project Manager
Funding: UF RESEARCH FOU

Education

Ph D. Psychology (clinical) and Psychophysiology
1994 · University of Delaware
Pre-doctoral Internship in Clinical Psychology
1994 · University of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic
M.A. Psychology (clinical)
1989 · University of Delaware
BS (Psychlogy/zoology)
1984 · University of Maryland, College Park

Contact Details

Phones:
Business:
(352) 273-6139
Emails:
Business:
wmp@phhp.ufl.edu
Addresses:
Business Mailing:
PO Box 100165
GAINESVILLE FL 32610
Business Street:
101 S NEWELL DR. RM. 3133
GAINESVILLE FL 326100001